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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5D
All Species:
26.97
Human Site:
S356
Identified Species:
42.38
UniProt:
Q14738
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14738
NP_006236.1
602
69992
S356
Q
F
L
E
K
E
S
S
L
T
E
P
V
I
V
Chimpanzee
Pan troglodytes
XP_518483
668
77639
S422
Q
F
L
E
K
E
S
S
L
T
E
P
V
I
V
Rhesus Macaque
Macaca mulatta
XP_001087636
549
63874
E332
V
M
F
L
N
E
L
E
E
I
L
D
V
I
E
Dog
Lupus familis
XP_538927
602
69962
S356
Q
F
L
E
K
E
S
S
L
T
E
P
V
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
L308
E
V
M
F
L
N
E
L
E
E
I
L
D
V
I
Rat
Rattus norvegicus
XP_001062510
563
65413
S335
K
F
W
P
K
T
H
S
P
K
E
V
M
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508677
454
52707
E238
M
F
L
N
E
L
E
E
I
L
D
V
I
E
P
Chicken
Gallus gallus
XP_419321
459
53699
R243
G
L
R
A
Y
V
R
R
Q
I
N
N
I
F
Y
Frog
Xenopus laevis
NP_001087638
506
58853
L290
S
I
I
N
G
F
A
L
P
L
K
E
E
H
K
Zebra Danio
Brachydanio rerio
NP_998483
601
69849
S343
Q
F
L
E
K
D
S
S
L
T
E
P
V
I
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138071
703
79051
S437
Q
F
L
E
K
D
P
S
L
S
E
A
V
I
K
Honey Bee
Apis mellifera
XP_392477
724
84384
S337
Q
F
L
E
K
D
P
S
L
T
E
P
V
I
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780420
579
66728
S331
Q
F
L
E
K
D
P
S
L
T
E
Q
V
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
E294
N
G
I
A
E
F
L
E
I
L
G
S
I
I
N
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
L529
Q
F
L
E
K
D
P
L
L
T
E
E
V
V
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
91
98.8
N.A.
69.9
92
N.A.
70.2
72.5
69.7
85.2
N.A.
56.9
57.1
N.A.
68.2
Protein Similarity:
100
90.1
91.1
99.3
N.A.
78
92.8
N.A.
72.7
74.5
77.5
92.1
N.A.
68.8
67.4
N.A.
79
P-Site Identity:
100
100
20
100
N.A.
0
26.6
N.A.
13.3
0
0
86.6
N.A.
66.6
80
N.A.
66.6
P-Site Similarity:
100
100
20
100
N.A.
26.6
46.6
N.A.
40
6.6
20
100
N.A.
80
86.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.8
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.4
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
0
0
7
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
34
0
0
0
0
7
7
7
0
0
% D
% Glu:
7
0
0
54
14
27
14
20
14
7
60
14
7
7
7
% E
% Phe:
0
67
7
7
0
14
0
0
0
0
0
0
0
14
0
% F
% Gly:
7
7
0
0
7
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% H
% Ile:
0
7
14
0
0
0
0
0
14
14
7
0
20
54
7
% I
% Lys:
7
0
0
0
60
0
0
0
0
7
7
0
0
0
14
% K
% Leu:
0
7
60
7
7
7
14
20
54
20
7
7
0
7
7
% L
% Met:
7
7
7
0
0
0
0
0
0
0
0
0
7
0
14
% M
% Asn:
7
0
0
14
7
7
0
0
0
0
7
7
0
0
7
% N
% Pro:
0
0
0
7
0
0
27
0
14
0
0
34
0
0
7
% P
% Gln:
54
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% Q
% Arg:
0
0
7
0
0
0
7
7
0
0
0
0
0
0
14
% R
% Ser:
7
0
0
0
0
0
27
54
0
7
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
7
0
0
0
47
0
0
0
0
0
% T
% Val:
7
7
0
0
0
7
0
0
0
0
0
14
60
14
20
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _